Scientific Publications

1: Du WJ, Chi Y, Yang ZX, Li ZJ, Cui JJ, Song BQ, Li X, Yang SG, Han ZB, Han ZC. Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta. Stem Cell Res Ther.2016 Nov 10;7(1):163. PubMed PMID: 27832825; PubMed Central PMCID: PMC5103372.

2: Du WJ, Reppel L, Leger L, Schenowitz C, Huselstein C, Bensoussan D, Carosella ED, Han ZC, Rouas-Freiss N. Mesenchymal Stem Cells Derived from Human Bone Marrowand Adipose Tissue Maintain Their Immunosuppressive Properties After ChondrogenicDifferentiation: Role of HLA-G. Stem Cells Dev. 2016 Oct 1;25(19):1454-69. doi:10.1089/scd.2016.0022. PubMed PMID: 27465875.

3: Liang L, Li Z, Ma T, Han Z, Du W, Geng J, Jia H, Zhao M, Wang J, Zhang B, Feng J, Zhao L, Rupin A, Wang Y, Han ZC. Transplantation of human placenta derived mesenchymal stem cell alleviates critical limb ischemia in diabetic nude rat.Cell Transplant. 2016 Aug 5. [Epub ahead of print] PubMed PMID: 27501782.

4: Du W, Li X, Chi Y, Ma F, Li Z, Yang S, Song B, Cui J, Ma T, Li J, Tian J, YangZ, Feng X, Chen F, Lu S, Liang L, Han ZB, Han ZC. VCAM-1+ placenta chorionic villi-derived mesenchymal stem cells display potent pro-angiogenic activity. Stem Cell Res Ther. 2016 Apr 4;7:49. doi: 10.1186/s13287-016-0297-0. PubMed PMID:27044487; PubMed Central PMCID: PMC4820943.

5: Chen F, Ma FX, Li Y, Xu FY, Chi Y, Lu SH, Han ZC. [Human Umbilical Cord-derived Mesenchymal Stem Cells Secrete Interleukin-6 to Influence Differentiation of Leukemic Cells]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2016 Apr;38(2):164-8. doi: 10.3881/j.issn.1000-503X.2016.02.007. Chinese. PubMed PMID:27181892.

6: Tao H, Han Z, Han ZC, Li Z. Proangiogenic Features of Mesenchymal Stem Cells and Their Therapeutic Applications. Stem Cells Int. 2016;2016:1314709. doi:10.1155/2016/1314709. Review. PubMed PMID: 26880933; PubMed Central PMCID:PMC4736816.

7: Ye XQ, Xie YM, Zou YH, Zhao XQ, Han JH, Wang XZ, Ma YZ, Bi Q, Xie QF, Zhao JJ,Cao XL, Chen HX, Wang Shi-zhong, Yan YM, Han ZC, Yi DH, Wang YY. [Effect of Naoshuantong capsule on change of SSQOL index in patients with ischemic stroke in six mouths follow-up]. Zhongguo Zhong Yao Za Zhi. 2015 Nov;40(21):4297-300.Chinese. PubMed PMID: 27071273.

8: Li B, Wang XJ, Liu YJ, Han ZC, Pang TX. [Soluble expression, purification and bioactivity of hemangiopoietin protein]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi.2009 Nov;25(11):991-3. Chinese. PubMed PMID: 19900364.

9: Zhang XG, Yang SG, Ren HY, Zhao QJ, Han ZC. [Effect of fetal lung mesenchymal stem cells on differentiation of umbilical cord blood mononuclear cells into megakaryocytes]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Oct;17(5):1312-5.Chinese. PubMed PMID: 19840473.

10: Liu M, Yang SG, Liu PX, DU WT, Gu DS, Lu SH, Xing W, Han ZC. [Comparative study of in vitro hematopoietic supportive capability of human mesenchymal stem cells derived from bone marrow and umbilical cord]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Oct;17(5):1294-300. Chinese. PubMed PMID: 19840470.

11: Sulpice E, Ding S, Muscatelli-Groux B, Bergé M, Han ZC, Plouet J, Tobelem G, Merkulova-Rainon T. Cross-talk between the VEGF-A and HGF signalling pathways in endothelial cells. Biol Cell. 2009 Sep;101(9):525-39. doi: 10.1042/BC20080221.PubMed PMID: 19281453.

12: Wu KH, Mo XM, Zhou B, Lu SH, Yang SG, Liu YL, Han ZC. Cardiac potential of stem cells from whole human umbilical cord tissue. J Cell Biochem. 2009 Aug 1;107(5):926-32. doi: 10.1002/jcb.22193. PubMed PMID: 19459155.

13: Fang ZH, Dong CL, Chen Z, Zhou B, Liu N, Lan HF, Liang L, Liao WB, Zhang L,Han ZC. Transcriptional regulation of survivin by c-Myc in BCR/ABL-transformed cells: implications in anti-leukaemic strategy. J Cell Mol Med. 2009 Aug;13(8B):2039-52. doi: 10.1111/j.1582-4934.2008.00549.x. PubMed PMID: 19602047.

14: Wang XX, Li YC, Ma XP, Han ZC. [Effects of electroacupuncture at Jiaji (EX-B 2) on extracellular matrix MMP-1, MMP-3 and TIMP-1 levels in the degenerated.cervical intervertebral disc in rats]. Zhen Ci Yan Jiu. 2009 Aug;34(4):248-51.Chinese. PubMed PMID: 19916288.

15: Liu PX, Zhang L, Liao WB, DU WT, Gu DS, Liu M, Lu SH, Han ZC. [Transfusion of allogeneic mesenchymal stem cells promotes progression of atherosclerotic plaque in rabbits]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Jun;17(3):700-5. Chinese.PubMed PMID: 19549391.

16: Zheng CL, Guo ZX, Han ZC, Zhou YL, Lu SH, Ren Q, Lu M. [Analysis on promoter CpG methylation and expression of HOXB4 gene in cord blood CD34(+) cells and peripheral blood mononuclear cells]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Jun;17(3):674-8. Chinese. PubMed PMID: 19549386.

17: Ma FX, Chen F, Ren Q, Han ZC. Lovastatin restores the function of endothelial progenitor cells damaged by oxLDL. Acta Pharmacol Sin. 2009 May;30(5):545-52.doi: 10.1038/aps.2009.41. PubMed PMID: 19417733; PubMed Central PMCID:PMC4002826.

18: Liu N, Lu M, Feng XM, Ma FX, Fang ZH, Tian XM, Ren Q, Zhang L, Liu B, Huang PP, Liu L, Han ZC. Exogenous Nanog alleviates but is insufficient to reverse embryonic stem cells differentiation induced by PI3K signaling inhibition. J Cell Biochem. 2009 Apr 15;106(6):1041-7. doi: 10.1002/jcb.22082. PubMed PMID:19229869.

19: Chen XL, Ren Q, Chen ZP, Zhou ZP, Zhao QJ, Qiu ZY, Dong CL, Han ZC. [Effect of silencing bmi-1 by RNA interference on function of K562 cell line]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Apr;17(2):266-70. Chinese. PubMed PMID: 19379548.

20: Han ZC. Umbilical cord mesenchymal stem cells (UC-MSC: biology, banking and clinical applications). Bull Acad Natl Med. 2009 Mar;193(3):545-7; discussion 547. PubMed PMID: 19883009.

21: Liao W, Xie J, Zhong J, Liu Y, Du L, Zhou B, Xu J, Liu P, Yang S, Wang J, Han Z, Han ZC. Therapeutic effect of human umbilical cord multipotent mesenchymal stromal cells in a rat model of stroke. Transplantation. 2009 Feb 15;87(3):350-9.doi: 10.1097/TP.0b013e318195742e. PubMed PMID: 19202439.

22: Chen XL, Dong CL, Feng XM, Chen ZP, Zhou ZP, Xu XH, Zhao QJ, Qiu ZY, Ren Q,Zhang L, Han ZC. [Expression of human factor IX in retrovirus-transfected human umbilical cord tissue derived mesenchymal stem cells]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Feb;17(1):184-7. Chinese. PubMed PMID: 19236775.

23: Liao W, Zhong J, Yu J, Xie J, Liu Y, Du L, Yang S, Liu P, Xu J, Wang J, Han Z, Han ZC. Therapeutic benefit of human umbilical cord derived mesenchymal stromal cells in intracerebral hemorrhage rat: implications of anti-inflammation and angiogenesis. Cell Physiol Biochem. 2009;24(3-4):307-16. doi:10.1159/000233255. PubMed PMID: 19710545.

24: Zheng C, Yang S, Guo Z, Liao W, Zhang L, Yang R, Han ZC. Human multipotent mesenchymal stromal cells from fetal lung expressing pluripotent markers and differentiating into cell types of three germ layers. Cell Transplant.2009;18(10):1093-109. doi: 10.3727/096368909X12483162197042. PubMed PMID:19650974.

25: Zhao Q, Ren H, Li X, Chen Z, Zhang X, Gong W, Liu Y, Pang T, Han ZC.Differentiation of human umbilical cord mesenchymal stromal cells into low immunogenic hepatocyte-like cells. Cytotherapy. 2009;11(4):414-26. doi:10.1080/14653240902849754. PubMed PMID: 19513901.

26: Li G, Zhang XA, Wang H, Wang X, Meng CL, Chan CY, Yew DT, Tsang KS, Li K,Tsai SN, Ngai SM, Han ZC, Lin MC, He ML, Kung HF. Comparative proteomic analysis of mesenchymal stem cells derived from human bone marrow, umbilical cord, and placenta: implication in the migration. Proteomics. 2009 Jan;9(1):20-30. doi:10.1002/pmic.200701195. PubMed PMID: 19116983.

27: He Y, Meng HX, Zhang YG, Hou SF, Wang H, Huang Y, Li Q, Han JL, Qiu LG, Han ZC. [Differences in megakaryocyte progenitor ex vivo expansion between CD34+ cells derived from human umbilical cord blood and bone marrow]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2008 Dec;16(6):1398-402. Chinese. PubMed PMID: 19099652.

28: Qiu ZY, Yang SG, Chen ZP, Zhao QJ, Chen XL, Zhou ZP, Yang RC, Han ZC.[Mesenchymal stem cells derived from human umbilical cord tissue modulate the secretion of antiplatelet antibody from splenocytes of ITP patients in vitro].Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2008 Dec;16(6):1372-5. Chinese. PubMed PMID: 19099646.

29: Han ZB, Ren H, Zhao H, Chi Y, Chen K, Zhou B, Liu YJ, Zhang L, Xu B, Liu B,Yang R, Han ZC. Hypoxia-inducible factor (HIF)-1 alpha directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF). Carcinogenesis. 2008 Oct;29(10):1853-61. doi:10.1093/carcin/bgn066. PubMed PMID: 18339685.

30: He Y, Meng HX, Zhang YG, Hou SF, Li Q, Han JL, Qiu LG, Han ZC. [Ex vivo expansion of megakaryocyte progenitors from human umbilical cord blood CD34(+) cells]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2008 Oct;16(5):1121-5. Chinese.PubMed PMID: 18928609.

31: Liu M, Han ZC. Mesenchymal stem cells: biology and clinical potential in type 1 diabetes therapy. J Cell Mol Med. 2008 Aug;12(4):1155-68. doi: 10.1111/j.1582-4934.2008.00288.x. Review. PubMed PMID: 18298656; PubMed CentralPMCID: PMC3865657.

32: Xu ZL, Wu YT, Sun Z, Zhu XF, Li R, Li HQ, Qi YM, Song JC, Han ZC. [Investigation on nutritional intakes for hospitalized children with blood disease]. Zhongguo Dang Dai Er Ke Za Zhi. 2008 Aug;10(4):467-70. Chinese. PubMed PMID: 18706163.

33: Feng XM, Liu N, Yang SG, Hu LY, Chen XL, Fang ZH, Ren Q, Lu SH, Liu B, Han ZC. Regulation of the class II and class I MHC pathways in human THP-1 monocytic cells by interleukin-27. Biochem Biophys Res Commun. 2008 Mar 14;367(3):553-9. doi: 10.1016/j.bbrc.2007.12.154. PubMed PMID: 18178151.

34: Lu L, Zhang L, Xiao Z, Lu S, Yang R, Han ZC. Neuropilin-1 in acute myeloid leukemia: expression and role in proliferation and migration of leukemia cells. Leuk Lymphoma. 2008 Feb;49(2):331-8. doi: 10.1080/10428190701809149. PubMed PMID:18231921.

35: Wu KH, Mo XM, Liu YL, Zhang YS, Han ZC. Stem cells for tissue engineering of myocardial constructs. Ageing Res Rev. 2007 Dec;6(4):289-301. Review. PubMed PMID: 17981518.

36: Xu ZL, Zhou B, Cong XL, Liu YJ, Xu B, Li YH, Gu J, Han ZC. Hemangiopoietin supports animal survival and accelerates hematopoietic recovery of chemotherapy-suppressed mice. Eur J Haematol. 2007 Dec;79(6):477-85. PubMed PMID:18021076.

37: Feng XM, Chen XL, Liu N, Chen Z, Zhou YL, Han ZB, Zhang L, Han ZC. Interleukin-27 upregulates major histocompatibility complex class II expression in primary human endothelial cells through induction of major histocompatibility complex class II transactivator. Hum Immunol. 2007 Dec;68(12):965-72. doi: 10.1016/j.humimm.2007.10.004. PubMed PMID: 18191724.

38: Huang PP, Yang XF, Li SZ, Wen JC, Zhang Y, Han ZC. Randomised comparison of G-CSF-mobilized peripheral blood mononuclear cells versus bone marrow-mononuclear cells for the treatment of patients with lower limb arteriosclerosis obliterans. Thromb Haemost. 2007 Dec;98(6):1335-42. PubMed PMID: 18064333.

39: Lu L, Zhang L, Xiao ZJ, Lu SH, Wang GS, Yang RC, Han ZC. [Expression and effect of neuropilin-1 in acute myeloid leukemic cells]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2007 Dec;15(6):1150-5. Chinese. PubMed PMID: 18088455.

40: Chen X, Xu J, Chen Z, Zhou Z, Feng X, Zhou Y, Ren Q, Yang R, Han ZC. Interferon-gamma +874A/T and interleukin-4 intron3 VNTR gene polymorphisms in Chinese patients with idiopathic thrombocytopenic purpura. Eur J Haematol. 2007 Sep;79(3):191-7. PubMed PMID: 17655693.

41: Zhou B, Liu PX, Lan HF, Fang ZH, Han ZB, Ren H, Poon MC, Han ZC. Enhancement  of neovascularization with mobilized blood cells transplantaion: supply of angioblasts and angiogenic cytokines. J Cell Biochem. 2007 Sep 1;102(1):183-95. PubMed PMID: 17390342.

42: Wu KH, Zhou B, Mo XM, Cui B, Yu CT, Lu SH, Han ZC, Liu YL. Therapeutic potential of human umbilical cord-derived stem cells in ischemic diseases. Transplant Proc. 2007 Jun;39(5):1620-2. PubMed PMID: 17580202.

43: Zhang L, Yang RC, Lu SH, Liu B, Ren H, Han ZB, Han ZC. [Role of antiapoptotic Bcl-X(L) in megakaryocyte differentiation and maturation]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2007 Jun;29(3):374-8. Chinese. PubMed PMID: 17633465.

44: Ma FX, Ren Q, Han ZC. [Effects of oxidized low-density lipoprotein on endothelial progenitor cells survival and activity mediated by lectin-like oxidized low density lipoprotein receptor]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2007 Jun;29(3):336-41. Chinese. PubMed PMID: 17633458.

45: Wu KH, Zhou B, Yu CT, Cui B, Lu SH, Han ZC, Liu YL. Therapeutic potential of human umbilical cord derived stem cells in a rat myocardial infarction model. Ann Thorac Surg. 2007 Apr;83(4):1491-8. PubMed PMID: 17383364

46: Zhou B, Gu DS, Liu PX, Zheng CL, Dong CL, Du WT, Wu KH, Han ZC. [Neovascularization potential of mobilized peripheral mononuclear cells from diabetes patients]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2007 Apr;29(2):262-7. Chinese. PubMed PMID: 17536281

47: Zhou B, Li S, Gu DS, Wu KH, Liu PX, Han ZC. [The therapeutic efficacy for limb ischemia by transplantation of mobilized peripheral blood cells before and after CD34+ cell depletion]. Zhonghua Xue Ye Xue Za Zhi. 2007 Mar;28(3):194-8. Chinese. PubMed PMID: 17649714.

48: Ma FX, Ren Q, Han ZC. [oxLDL reduced endothelial progenitor cells survival and function via regulating Akt/eNOS signal pathway]. Zhonghua Xin Xue Guan Bing Za Zhi. 2007 Feb;35(2):173-7. Chinese. PubMed PMID: 17445417.